Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling

Journal article

Open access

Peer reviewed

Manjari Singh, Sweta Kasna, Subhadeep Roy, Sara Aldosary, Abdulaziz S. Saeedan, Mohd. Nazam Ansari and Gaurav Kaithwas

BMC cancer, Vol.19(1), pp.996-996

24/10/2019

PMCID: PMC6814136

PMID: 31651285

Abstract

DuCLOX

ER+ mammary gland cancer

Mitochondrial stress

N-methyl-n-nitrosourea

PDE-5 inhibitor

Tadalafil

url

https://doi.org/10.1186/s12885-019-6152-9View

Published (Version of record) Open

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Title: Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling
Creators - without role: Manjari Singh - Babasaheb Bhimrao Ambedkar University
Sweta Kasna - Babasaheb Bhimrao Ambedkar University
Subhadeep Roy - Babasaheb Bhimrao Ambedkar University
Sara Aldosary - King Faisal University
Abdulaziz S. Saeedan - Prince Sattam Bin Abdulaziz University
Mohd. Nazam Ansari - Prince Sattam Bin Abdulaziz University
Gaurav Kaithwas - Babasaheb Bhimrao Ambedkar University
Publication Details: BMC cancer, Vol.19(1), pp.996-996
Publisher: BioMed Central
Grant note: RGNF-2013-14-SC-UTT-38150 / ;
Identifiers: 9919972108331
Academic Unit: King Faisal University
Language: English
Resource Type: Journal article