Abstract
Background: Amelogenesis imperfecta (AI) comprises a group of hereditary disorders affecting the structure of enamel. Although many etiological factors have been implicated for the cause of these disorders, some of the systemic conditions such as asthma and dietary factors like intake of soft drinks have been correlated with AI.Case presentation: This work is a clinical report of a 14-year-old girl who was diagnosed with hypoplastic type of AI. The patient had a history of asthma and she complained of dry mouth. She required replacement of her stainless steel crowns and wanted esthetic smile. In addition, she was advised composite restorations and fabrication of removable overlay upper and lower dentures.Conclusion: The current case report implicated that AI could be associated with conditions such as asthma; However, future research on molecular, functional, and genetic aspects of AI integrating the inflammatory response of Asthma may help in preventing the enamel defects. Implementation of dental care for this structured population may help in preventing dental complication due to increased risk.