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Rh-catalyzed oxidizing group-directed ortho C-H vinylation of arenes by vinylstannanes
Journal article   Peer reviewed

Rh-catalyzed oxidizing group-directed ortho C-H vinylation of arenes by vinylstannanes

Sekar Prakash, Krishnamoorthy Muralirajan and Chien-Hong Cheng
Chemical communications (Cambridge, England), Vol.51(69), pp.13362-13364
07/09/2015
PMID: 26106954

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
An efficient method for the synthesis of functionalized vinyl arenes from the reaction of N-methoxybenzamides or N-phenoxyacetamides with vinylstannanes via rhodium(III)-catalyzed C-H activation is described. The application of the methodology for the synthesis of a natural product thalactamine and a 7-membered ring oxepine are also demonstrated.

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