Abstract
In the present study, thirty patients in the age range of 22 to 63 years of age were included after being diagnosed to be having brain tumour on CT scan or conventional MRI. In addition DWI, MRS, and PWI were carried out in these patients. All the patients with suspicious malignant lesions were then subjected to FDG-PET examination. Histopathological correlation was obtained in all the patients to serve as gold standard against which other modalities will be assessed for their sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy. Out of thirty patients selected for this study, twenty cases were found to be malignant and ten cases were benign on Histopathological evaluation. Majority of malignant lesions were glioblastoma multiforme. Amongst benign cases, majorities were meningioma, one was a Granulomatous lesion and one was a benign cystic lesion. MRI including the novel techniques showed high sensitivity and specificity in identifying malignant brain lesions and has a future role in better characterization of brain tumours. Wherever available, it should be integrated in routine workup of patients presenting with brain tumours or for follow up of patients undergone surgery / adjuvant chemotherapy.