Abstract
This review is aiming to review and analysis the Substance abuse risk factors. The present review was conducted by searching in Medline, Embase, Web of Science, Science Direct, BMJ journal and Google Scholar for, researches, review articles and reports, published over the past years. Books published on the Substance abuse risk factors. If several studies had similar findings, we randomly selected one or two to avoid repetitive results. Based on findings and results this review found Adolescents are particularly susceptible to involvement in substance use due to the underdeveloped state of the adolescent brain, also social, individual, peer, family, and the community factors play significant role as risk factors for the occurrence of the Substance abuse and its disorders.