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SYNTHESIS AND ANTIMICROBIAL EVALUATION OF NEW PYRAZOLE, THIOPHENE, THIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES INCORPORATING PYRIMIDINE RING
Journal article   Peer reviewed

SYNTHESIS AND ANTIMICROBIAL EVALUATION OF NEW PYRAZOLE, THIOPHENE, THIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES INCORPORATING PYRIMIDINE RING

Ahmad M. Farag, Nabila A. Kheder and Yahia N. Mabkhot
Heterocycles, Vol.78(7), pp.1787-1798
01/07/2009
DOI: https://doi.org/10.3987/COM-09-11682

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The utility of 3-oxo-N-(pyrimidin-2-yl)butanamide (1) in the synthesis of some new pyrazole, thiophene, thiazole, and 1,3,4-thiadiazole derivatives pendant to a pyrimidine ring is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed moderate activity.

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