Abstract
Several new heterocyclic compounds such as chromene, pyrazole, isoxazole, dihydropyridine, thiazole, thiophene, pyrazolopyridine and pyrimidobenzimidazole derivatives have been synthesized by the reactions of the versatile multifunctional unreported 3-(4-methyl-2-(tosylamino)thiazol-5-yl)-3-oxopropanenitrile with several nitrogen binucleophiles. A one-pot three component reaction of an aldehyde, the 3-oxopropanenitrile derivative, and electron-rich heterocyclic amines has been decribed.