A regioselective formation of ethyl pyrrole-2-carboxylates 4 and 5 is effected by reductive condensation of enaminones 1a-f and ethyl 2-oximinoacetoacetate 2. The structures of the products have been delineated by spectroscopic methods.
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Title
SYNTHESIS OF ETHYL PYRROLE-2-CARBOXYLATES: A REGIOSELECTIVE CYCLIZATION OF ENAMINONES UNDER KNORR-TYPE CONDITIONS
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Ibrahim Elghamry - Division of Organic Chemistry, FB6 , Gerhard-Mercator-University Duisburg , Duisburg, D-47048, Germany