Abstract
The hydrazide of 2′-thienoyl anthranilic acid and its 3,5-dibromo derivative (1a and b) were condensed with carbon disulphide to give 1-3′-quinazolin-2-thione 5-2′′-aminophenyl-1,3,4-triazoles (2a, b). When treated with acetyl chloride 3-N-acetamidoquinazolin-4-ones (3a, b), with aromatic aldehydes the schiff bases 4 and 5(a, b). Potassium thiocyanate and phenyl isothiocyanate gave the semicarbazide derivatives (6a, b) while ammonium thiocyanate afforded the triazol-thiones (7a, b). Reaction with ethyl acetoacetate and acetylacetone gave the pyrazole derivatives 8 and 9 respectively; Biological activities of some of these compounds are tested.