Abstract
In search for bioactive compounds from
Sabal species, sablacaurin A [25-ethyl,23-methyl-19-
nor-24-methylene-3,4-
seco-4(28)-lanosten-10,3-olide] and sablacaurin B [24-ethyl,24-methyl-19-
nor-3,4-
seco-4(28),25(26)-lanostadiene-10,3-olide], the first 19-
nor lanostane derivatives of the 3,4-
seco type with a spiro element, have been isolated from the leaves of
Sabal causiarum and
Sabal blackburniana respectively, together with the known squalene (
S. blackburniana) and ß-sitosterol (
S. causiarum). From leaves of
Sabal peregrina, the known triterpenes 3-oxo-24-methylenecycloartane and 24-methylcycloart-25(26)-en-3-one were isolated. The structures of these compounds were established from spectroscopic studies.
Sablacaurin A [25-ethyl,23-methyl-19-
nor-24-methylene-3,4-
seco-4(28)-lanosten-10,3-olide] and sablacaurin B [24-ethyl,24-methyl-19-
nor-3,4-
seco-4(28),25(26)-lanostadiene-10,3-olide], the first 19-
nor lanostane derivatives of the 3,4-
seco type with a spiro element, have been isolated from the leaves of
Sabal causiarum and
Sabal blackburniana respectively.