Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor

Maha-Hamadien Abdulla; Kee-Chong Lim; Mohammed Sajid; James H McKerrow; Conor R Caffrey

doi:10.1371/journal.pmed.0040014

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Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor

Journal article

Open access

Peer reviewed

Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor

Maha-Hamadien Abdulla, Kee-Chong Lim, Mohammed Sajid, James H McKerrow and Conor R Caffrey

PLoS medicine, Vol.4(1), pp.0130-0138

01/01/2007

DOI: https://doi.org/10.1371/journal.pmed.0040014

PMCID: PMC1764436

PMID: 17214506

Abstract

Biochemistry

Drugs and adverse drug reactions

Infectious Diseases

Medicine in Developing Countries

Microbiology

A significant reduction in parasite burden and pathology by a vinyl sulfone cysteine protease inhibitor suggests a new direction for chemotherapy of human schistosomiasis.

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Title: Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor
Creators - without role: Maha-Hamadien Abdulla - QB3
Kee-Chong Lim - QB3
Mohammed Sajid - QB3
James H McKerrow - University of California, San Francisco
Conor R Caffrey - QB3
Publication Details: PLoS medicine, Vol.4(1), pp.0130-0138
Publisher: Public Library of Science
Identifiers: 9949253708331
Academic Unit: King Saud University
Language: English
Resource Type: Journal article