Abstract
Currently available anticancer drugs are cytotoxic to normal as well as to neoplastic cells, therefore the synthesis of beta-lactams as new and novel anticancer agents is extremely significant. We previously developed synthetic methods for the preparation of beta-lactams and anticancer agents resulting from polyaromatic amines. There have also been reports on the synthesis and biological evaluation of novel racemic beta-lactams Lis anticancer agents. In cell cycle analysis, these compounds demonstrated a G2 blockage against sensitive tumor cell lilies. In the present Study, useful and selective biological activities of chrysene beta-lactams are described.