Abstract
A novel chemosensor based on Nifuroxazide Cr(III) complex was developed for recognizing CN- over other tested anions e.g., F -, Cl -, Br -, I -, CH3COO -, NO2 -, PO4 3-, and SCN- in DMSO-H2O (9:1, v/v) and THF. Without any interference from the tested anions, UV-vis spectroscopy was used to investigate the recog-nition of CN-. The deprotonated species that resulted from the ionization of the phenolic group may be the cause of the color shift that occurred after adding CN- to the solution of the Cr(III) complex. The charge transfer interaction between the electron-donor unit and the electron-deficient nitro-furan moiety was improved as a result of the ionization of the phenolic group. The fact that the developed color van-ishes in protic polar solvents e.g., H2O, CH3OH, and C2H5OH may lend credence to this assumption. The Lambert-Beer's law was obeyed in the concentration ranges of 3.4 x 10 -3 -3.4 x 10 -5 M and 1.0 x 10 -4- 5.0 x 10 -6 M in DMSO-H2O (9:1, v/v) and THF, respectively, reflecting the significant role of the solvent in controlling the sensitivity of the developed probe. The electronic transitions were investigated by exe-cuting time-dependent density functional theory calculations.(c) 2023 Elsevier B.V. All rights reserved.