Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of beta-amyloid aggregates

P. A. T. Martins; S. Alsaiari; K. Julfakyan; Z. Nie; N. M. Khashab

doi:10.1039/c6cc09085k

Back

Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of beta-amyloid aggregates

Journal article

Peer reviewed

Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of beta-amyloid aggregates

P. A. T. Martins, S. Alsaiari, K. Julfakyan, Z. Nie and N. M. Khashab

Chemical communications (Cambridge, England), Vol.53(13), pp.2102-2105

09/02/2017

DOI: https://doi.org/10.1039/c6cc09085k

PMID: 28098266

Abstract

Chemistry

Chemistry, Multidisciplinary

Physical Sciences

Science & Technology

We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.

Metrics

1 Record Views

See more details

Details

Title: Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of beta-amyloid aggregates
Creators - without role: P. A. T. Martins - King Abdullah University of Science and Technology
S. Alsaiari - King Abdullah University of Science and Technology
K. Julfakyan - King Abdullah University of Science and Technology
Z. Nie - University of Maryland, College Park
N. M. Khashab - King Abdullah University of Science and Technology
Publication Details: Chemical communications (Cambridge, England), Vol.53(13), pp.2102-2105
Publisher: Royal Soc Chemistry
Number of pages: 4
Identifiers: 9943981608331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article