Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity

M. G. Hemida; R. A. Perera; R. A. Al Jassim; G. Kayali; L. Y. Siu; P. Wang; K. W. Chu; S. Perlman; M. A. Ali; A. Alnaeem; Y. Guan; L. L. Poon; L. Saif; M. Peiris

doi:10.2807/1560-7917.ES2014.19.23.20828

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Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity

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Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity

M. G. Hemida, R. A. Perera, R. A. Al Jassim, G. Kayali, L. Y. Siu, P. Wang, K. W. Chu, S. Perlman, M. A. Ali, A. Alnaeem, …

Euro surveillance : bulletin européen sur les maladies transmissibles, Vol.19(23), pp.2-7

12/06/2014

DOI: https://doi.org/10.2807/1560-7917.ES2014.19.23.20828

PMID: 24957744

Abstract

Infectious Diseases

Life Sciences & Biomedicine

Science & Technology

The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.

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Title: Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity
Creators - without role: M. G. Hemida - Kafrelsheikh University
R. A. Perera - University of Hong Kong
R. A. Al Jassim - University of Queensland
G. Kayali - St. Jude Children's Research Hospital
L. Y. Siu - HKU-Pasteur Research Pole
P. Wang - HKU-Pasteur Research Pole
K. W. Chu - University of Hong Kong
S. Perlman - University of Iowa
M. A. Ali - National Research Centre
A. Alnaeem - King Faisal University
Y. Guan - University of Hong Kong
L. L. Poon - University of Hong Kong
L. Saif - The Ohio State University
M. Peiris - University of Hong Kong
Publication Details: Euro surveillance : bulletin européen sur les maladies transmissibles, Vol.19(23), pp.2-7
Publisher: Eur Centre Dis Prevention & Control
Number of pages: 6
Grant note: 143011 / Deanship of Research of the College of Veterinary Medicine, King Faisal University 223498 / European Community under project European management Platform for Emerging and Re-emerging Disease entities (EMPERIE) HHSN266200700005C / National Institute of Allergy and Infectious Diseases, National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
Identifiers: 9920296008331
Academic Unit: King Faisal University
Language: English
Resource Type: Journal article