Abstract
Serum immunoglobulin concentrations were determined in 19 patients with cancer of the cervix and 49 healthy control women matched for age and parity. A significantly greater number of the cancer patients showed evidence of high levels (greater than mean ± 2 SD of the healthy control levels) of IgG and IgA, but not the IgM levels, as compared with the healthy controls. The possibility that these raised serum immunoglobulins are specific for tumor-antigens contained within or on the surface of malignant cells was discussed.