Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Sachiyo Yoshida; Jose Martines; Joy E. Lawn; Stephen Wall; Joao Paulo Souza; Igor Rudan; Simon Cousens; Peter Aaby; Ishag Adam; Ramesh Kant Adhikari; Namasivayam Ambalavanan; Shams El Arifeen; Dhana Raj Aryal; Sk Asiruddin; Abdullah Baqui; Aluisio J. D. Barros; Christine S. Benn; Vineet Bhandari; Shinjini Bhatnagar; Sohinee Bhattacharya; Zulfiqar A. Bhutta; Robert E. Black; Hannah Blencowe; Carl Bose; Justin Brown; Christoph Buehrer; Wally Carlo; Jose Guilherme Cecatti; Po-Yin Cheung; Robert Clark; Tim Colbourn; Agustin Conde-Agudelo; Erica Corbett; Andrew E. Czeizel; Abhik Das; Louise Tina Day; Carolyn Deal; Ashok Deorari; Ugur Dilmen; Mike English; Cyril Engmann; Fabian Esamai; Caroline Fall; Donna M. Ferriero; Peter Gisore; Tabish Hazir; Rosemary D. Higgins; Caroline S. E. Homer; D. E. Hoque; Lorentz Irgens; M. T. Islam; Joseph de Graft-Johnson; Martias Alice Joshua; William Keenan; Soofia Khatoon; Helle Kieler; Michael S. Kramer; Eve M. Lackritz; Tina Lavender; Laurensia Lawintono; Richard Luhanga; David Marsh; Douglas McMillan; Patrick J. McNamara; Ben Willem J. Mol; Elizabeth Molyneux; G. K. Mukasa; Miriam Mutabazi; Luis Carlos Nacul; Margaret Nakakeeto; Indira Narayanan; Bolajoko Olusanya; David Osrin; Vinod Paul; Christian Poets; Uma M. Reddy; Mathuram Santosham; Rubayet Sayed; Natalia E. Schlabritz-Loutsevitch; Nalini Singhal; Mary Alice Smith; Peter G. Smith; Sajid Soofi; Catherine Y. Spong; Shahin Sultana; Antoinette Tshefu; Frank van Bel; Lauren Vestewig Gray; Peter Waiswa; Wei Wang; Sarah L. A. Williams; Linda Wright; Anita Zaidi; Yanfeng Zhang; Nanbert Zhong; Isabel Zuniga; Rajiv Bahl; Neonatal Hlth Res Priority Setting

doi:10.7189/jogh.06.010508

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Setting research priorities to improve global newborn health and prevent stillbirths by 2025

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Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Sachiyo Yoshida, Jose Martines, Joy E. Lawn, Stephen Wall, Joao Paulo Souza, Igor Rudan, Simon Cousens, Peter Aaby, Ishag Adam, Ramesh Kant Adhikari, …

Journal of global health, Vol.6(1), pp.010508-010508

01/06/2016

DOI: https://doi.org/10.7189/jogh.06.010508

PMCID: PMC4576458

PMID: 26401272

Abstract

Life Sciences & Biomedicine

Public, Environmental & Occupational Health

Science & Technology

Background In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025. Methods We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts. Results Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour. Conclusion These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed

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Title: Setting research priorities to improve global newborn health and prevent stillbirths by 2025
Creators - without role: Sachiyo Yoshida - World Hlth Org, Newborn Child & Adolescent Hlth, Dept Maternal, 20 Ave Appia, CH-1211 Geneva 27, Switzerland
Jose Martines - University of Bergen
Joy E. Lawn - Supreme Council Of Health
Stephen Wall - Save Children, Saving Newborn Lives, Washington, DC USA
Joao Paulo Souza - Supreme Council Of Health
Igor Rudan - University of Edinburgh
Simon Cousens - Supreme Council Of Health
Peter Aaby - Bandim Hlth Project Indepth Network, Bissau, Guinea Bissau
Ishag Adam - University of Khartoum
Ramesh Kant Adhikari - College Station Medical Center
Namasivayam Ambalavanan - University of Alabama
Shams El Arifeen - Int Ctr Diar rhoeal Dis Res, Ctr Child & Adolescent Hlth, Dhaka, Bangladesh
Dhana Raj Aryal - Paropakar Matern & womens Hosp, Dept Neonatol, Kathmandu, Nepal
Sk Asiruddin - University Research Co
Abdullah Baqui - Supreme Council Of Health
Aluisio J. D. Barros - Univ Fed Pelotas, Ctr Pesquisas Epidemiol, Pelotas, Brazil
Christine S. Benn - University of Southern Denmark
Vineet Bhandari - Yale University
Shinjini Bhatnagar - Translat Hlth Sci & Technol Inst, Pediat Biol Ctr, Pali, India
Sohinee Bhattacharya - University of Aberdeen
Zulfiqar A. Bhutta - Aga Khan University
Robert E. Black - Supreme Council Of Health
Hannah Blencowe - Supreme Council Of Health
Carl Bose - Supreme Council Of Health
Justin Brown - Thrasher Research Fund
Christoph Buehrer - Charles University
Wally Carlo - University of Alabama
Jose Guilherme Cecatti - Supreme Council Of Health
Po-Yin Cheung - University of Alberta
Robert Clark - Charities, New Orleans, LA USA
Tim Colbourn - Univ Coll London Inst Global Hlth, London, England
Agustin Conde-Agudelo - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Perinatol Res Branch, Natl Inst Hlth, Dept Hlth & Human Serv, Bethesda, MD USA
Erica Corbett - Independent consultant maternal Hlth Res, Kigali, Rwanda
Andrew E. Czeizel - Fdn Commun Control Hereditary Dis, Budapest, Hungary
Abhik Das - RTI Int, Biostatist & Epidemiol, Res Triangle Pk, NC USA
Louise Tina Day - LAMB Integrated Rural Hlth & Dev, Dinajpur, Bangladesh
Carolyn Deal - Natl Inst Allergy & Infect Dis Natl Inst Hlth, Div Microbiol & Infect Dis, Salt Lake City, UT USA
Ashok Deorari - College Station Medical Center
Ugur Dilmen - Ankara
Mike English - University of Oxford
Cyril Engmann - Gates
Fabian Esamai - Moi University
Caroline Fall - University of Southampton
Donna M. Ferriero - UCSF Benioff Childrens Hosp, Dept Pediat, San Francisco, CA USA
Peter Gisore - Moi University
Tabish Hazir - College Station Medical Center
Rosemary D. Higgins - Eunice Kennedy Shriver NICHD Neonatal Res Network, Pregnancy & Perinatol Branch, Natl Inst Hlth, Bethesda, MD USA
Caroline S. E. Homer - Univ Technol, Ctr Midwifery Child & Family Hlth, Sydney, NSW, Australia
D. E. Hoque - Int Ctr Diarrhoeal Dis Res, Ctr Child & Adolescent Hlth, Dhaka, Bangladesh
Lorentz Irgens - University of Bergen
M. T. Islam - Japan Int Cooperat Agcy JICA, Dhaka, Bangladesh
Joseph de Graft-Johnson - Save Children, Fairfield, CT USA
Martias Alice Joshua - Zomba Cent Hosp, Minist Hlth, Zomba, Malawi
William Keenan - St Louis Univ, St Louis, MO USA
Soofia Khatoon - College Station Medical Center
Helle Kieler - Karolinska Institutet
Michael S. Kramer - McGill University
Eve M. Lackritz - Global Alliance Prevent Prematur & Stillbirth GAP, Seattle, WA USA
Tina Lavender - University of Manchester
Laurensia Lawintono - Indonesian Midw Assoc, Jakarta, Indonesia
Richard Luhanga - Save Children, Lilongwe, Malawi
David Marsh - Save Children, Fairfield, CT USA
Douglas McMillan - Dalhousie University
Patrick J. McNamara - University of Toronto
Ben Willem J. Mol - College Station Medical Center
Elizabeth Molyneux - College Station Medical Center
G. K. Mukasa - ACT
Miriam Mutabazi - STRIDES Family Hlth, Management Sci Hlth, Kampala, Uganda
Luis Carlos Nacul - Supreme Council Of Health
Margaret Nakakeeto - Kampala Childrens Hosp Ltd & Childhealth Advocacy, Kampala, Uganda
Indira Narayanan - United States Agcy Int Dev, Maternal & Child Hlth Integrated Program, Washington, DC USA
Bolajoko Olusanya - Healthy Start
David Osrin - Wellcome Trust
Vinod Paul - College Station Medical Center
Christian Poets - University of Tübingen
Uma M. Reddy - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Dev Natl Inst Hlth, Cambridge, MD USA
Mathuram Santosham - Supreme Council Of Health
Rubayet Sayed - Save Children, Dhaka, Bangladesh
Natalia E. Schlabritz-Loutsevitch - University of Tennessee at Knoxville
Nalini Singhal - University of Calgary
Mary Alice Smith - Univ Georgia, Dept Environm Hlth Sci, Athens, GA 30602 USA
Peter G. Smith - Supreme Council Of Health
Sajid Soofi - Aga Khan University
Catherine Y. Spong - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, NIH, Bethesda, MD USA
Shahin Sultana - Minist Hlth & Family Welf, Natl Inst Populat Res & Training NIPORT, Dhaka, Bangladesh
Antoinette Tshefu - University of Kinshasa
Frank van Bel - Univ Utrecht, Dept Neonatol, Utrecht, Netherlands
Lauren Vestewig Gray - Rice University
Peter Waiswa - Karolinska Institutet
Wei Wang
Sarah L. A. Williams - Edith Cowan University
Linda Wright - Supreme Council Of Health
Anita Zaidi - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, NIH, Bethesda, MD USA
Yanfeng Zhang - Capital University
Nanbert Zhong - New York State Inst Basic Res Dev Disabil, Lab Dev Genet, New York, NY USA
Isabel Zuniga - Medecins Sans Frontieres, Brussels, Belgium
Rajiv Bahl - World Hlth Org, Newborn Child & Adolescent Hlth, Dept Maternal, 20 Ave Appia, CH-1211 Geneva 27, Switzerland
Neonatal Hlth Res Priority Setting
Publication Details: Journal of global health, Vol.6(1), pp.010508-010508
Publisher: Univ Edinburgh, Global Health Soc
Number of pages: 10
Grant note: MC_UP_A620_1016 / Medical Research Council; UK Research & Innovation (UKRI); Medical Research Council UK (MRC); European Commission MC_UU_12011/3 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) Save the Children
Identifiers: 9928930708331
Academic Unit: Qassim University
Language: English
Resource Type: Journal article