Abstract
Shape memory polymers (SMPs) are emerging smart materials that have the ability to change to a shape and revert to their permanent shape on application of external stimulus. SMPs can be divided into four types based on their permanent shape, elasticity origin, and temporary shape fixing mechanism: chemically cross-linked glassy thermosets, chemically cross-linked semi-crystalline, physically cross-linked glassy copolymers, and physically cross-linked block copolymers. The broad overview of recent developments on SMPs for biomedical applications proves their wide applicability in the field of general medicine, drug delivery, regenerative medicine, dentistry, neuromedicine, cancer therapy, orthopedics, and corrosion protection. Herein, a comprehensive analysis of SMPs and their composites with focus on their types, mechanism, functionality and biomedical applications is presented. Relevant biomedical technologies based on SMPs and their future advancement towards biomedical applications are also discussed.