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Simple, Three-Component, Highly Efficient Green Synthesis of Thiazolo[3,2-a]pyridine Derivatives Under Neat Conditions
Journal article   Peer reviewed

Simple, Three-Component, Highly Efficient Green Synthesis of Thiazolo[3,2-a]pyridine Derivatives Under Neat Conditions

Ramadan Ahmed Mekheimer, Noha Mohamed Hilmy, Afaf Abdel Hameed, Sawsan Dacrory and Kamal Usef Sadek
Synthetic communications, Vol.41(17), pp.2511-2516
01/09/2011

Abstract

Neat conditions thiazolo[3,2-a]pyridines three component
Green, highly efficient, three-component syntheses of thiazolo-[3,2-a]pyridine derivatives via reaction of malononitrile, aromatic aldehydes, and 2-mercaptoacetic acid with a catalytic amount of piperidine without solvent with molar ratios of 2:2:1.2 and 2:2.2:1, respectively, has been reported.

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