O-Acylation of N-Boc-protected-serine and -threonine with N-Pg-(alpha-aminoacyl)benzotriazoles afforded the chiral O-acylated isodipeptides at 23 degrees C in yields of 74-91%.
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Details
Title
Solution-phase synthesis of chiral O-acyl isodipeptides
Creators - without role
Mirna El Khatib - University of Florida
Lilibeth Jauregui - University of Florida
Srinivasa R. Tala - University of Florida
Levan Khelashvili - University of Florida
Alan R. Katritzky - University of Florida
Publication Details
MedChemComm, Vol.2(11), pp.1087-1092
Publisher
Royal Soc Chemistry
Number of pages
6
Grant note
University of Florida
Kenan Foundation
King Abdulaziz University, Jeddah, Saudi Arabia