Abstract
•A facile sonochemical method was used for the synthesis of CuFe2O4/C3N4 nanocomposite.•CuFe2O4/C3N4 modified SPCE was used as a non-enzymatic xanthine sensor.•DPV shows the sensor to have a wide linear range and low detection limit.•The practical application of the CuFe2O4/C3N4 modified sensor was studied by DPV.
A novel network-like magnetic nanoparticle was fabricated on a graphitic carbon nitride through a facile sonochemical route at frequency 20 kHz and power 70 W. To enhance the electrocatalytic activity of the modified materials, the graphitic carbon nitrides (g-C3N4) was prepared from melamine. Monitoring of xanthine concentration level in biological fluids is more important for clinical diagnosis and medical applications. As modified CuFe2O4/g-C3N4 nanocomposite exhibits better electrochemical activity towards the oxidation of xanthine with higher anodic current compared to other modified and unmodified electrode for the detection of xanthine with larger linear range (0.03–695 µM) and lower limit of detection (13.2 nM). To compare with these methods, the electrochemical techniques may be an alternative high sensitive method due to their simplicity and rapid detection time. In addition, the practical feasibility of the sensor was inspected with biological samples, reveals the acceptable recovery of the sensor in real samples.