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Spectral Discrimination of Benign and Malignant Prostate Tissues-A Preliminary Report
Journal article   Peer reviewed

Spectral Discrimination of Benign and Malignant Prostate Tissues-A Preliminary Report

Vadivel Masilamani, Danny Rabah, Mohamed AlSalhi, Vijmasi Trinka and Parthasarathy VijayaRaghavan
Photochemistry and photobiology, Vol.87(1), pp.208-214
01/01/2011
PMID: 21091483

Abstract

Biochemistry & Molecular Biology Biophysics Life Sciences & Biomedicine Science & Technology
In this preliminary report, benign (n = 8) and malignant (n = 5) prostate tissues, in vitro, have been taken through autofluorescence spectroscopy. Employing Stokes' shift spectra and fluorescence emission spectra as tools of analysis, we were able to discriminate the two sets of tissues with sensitivity and specificity in excess of 85%. When the excised prostate chips were scanned with a spatial resolution of 1 mm, the epicenter of malignancy also could be delineated.

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