Abstract
We reported a spectrophotometric method for the determination of norfloxacin. The method is based on the reaction of the drug with bromophenol blue in acetate buffer at pH 4.1 and measurement of the yellow complex formed at 416 nm. Linear calibration graph was obtained from 5 to 150 ppm of norfloxacin with percentage relative standard deviation of less than 2% (n=6), the correlation coefficient r = 0.9998. The method was applied successfully to drug analysis. (C) 2019 Published by Elsevier B.V. on behalf of King Saud University.