Abstract
Aim: To examine the efficacy of oral versus intravenous medicine in treatment of spontaneous bacterial peritonitis.
Study design: Comparative/Observational study.
Place and duration: This study was conducted in a Rural Area of Lahore at Rehber Medical and Dental College, Lahore from 01-01-2017 to 31-12-2017.
Methods: 160 patients of both gender having SBP due to cirrhosis was included in this study. Patient's ages were ranging from 20 to 70 years. Patients' detailed medical history, including age sex socio-economic status was examined after taking informed consent from all the patients. Patients were equally divided in two groups, i.e. (Group O) oral and (Group IV) intravenous. Strong follow-up was taken from all the patients.
Results: From all 160 patients, 100(62.5%) patients were men while 37.5% patients were women. 42(26.25%) patients had ages 20 to 34 years, 54(33.75%) patients were ages between 35 to 49 years, 45(28.13%) patients were ages between 50 to 64 years and 19(11.86%) patients had ages greater than 64 years. 90(56.25%) patients had rural residency. There were 80 patients in each group. In Group O, there were 52 males and 28 females while in IV group, there were 48 males and 32 females. Spontaneous bacterial peritonitis eliminated in 72(90%) in oral antibiotics treated patients and 76(95%) in IV treated patients. Mortality found in 2(2.50%) patient in oral group and 3(3.75%) in IV group.
Conclusion: It is concluded that the efficacy and mortality rate of oral and intravenous antibiotics for treatment of spontaneous bacterial peritonitis was similar. No major difference was observed.