Abstract
Bilateral neuroblastoma requires treatment according to the development of lesion. Objective: A two -month-old female infant presented with bilateral adrenal masses and marked hepatomegaly owing to diffuse hepatic metastatic lesions. A provisional diagnosis of bilateral adrenal neuroblastoma was made with computed tomography (CT), followed by metaiodobenzylguanidine scintigraphy, and thereafter was confirmed histopathologically. A follow-up ultrasound examination performed 1.5 years after diagnosis showed stage 4S behavior of the disease, which involved spontaneous resolution of the adrenal masses. Conclusion: This finding supports the idea that bilateral disease must be staged separately in order to select the best treatment plan and to explore any possible associated prognostic factors.