Sign in
Back
Stereoselective crossed-aldol condensation of 3-acetyl-2,5-dimethylthiophene/furan with aromatic aldehydes in water: Synthesis of (2E)-3-aryl-1-(thien-3-yl/fur-3-yl)-prop-2-en-1-ones
Journal article   Peer reviewed

Stereoselective crossed-aldol condensation of 3-acetyl-2,5-dimethylthiophene/furan with aromatic aldehydes in water: Synthesis of (2E)-3-aryl-1-(thien-3-yl/fur-3-yl)-prop-2-en-1-ones

Mohamed A. Hassan, Suzan Batterjee and Layla A. Taib
Indian journal of chemistry. Sect. B. Organic chemistry, including medicinal chemistry, Vol.45(8), pp.1936-1941
01/08/2006

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Aldol condensation of 3-acetyl-2, 5-dimethylthiophene I and 3-acetyl-2, 5-dimethylfuran 2 with different aromatic aldehydes have been carried out in water in heterogeneous phases in the presence of cetyltritnethylammonium bromide as cationic surfactant at rt. All the reactions occur in short time with excellent yields of steroselective heteroarylpropenones with water as environmental friendly solvent.

Metrics

1 Record Views

Details