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Stereoselective synthesis of beta-lactams under diverse conditions: Unprecedented observations
Journal article   Peer reviewed

Stereoselective synthesis of beta-lactams under diverse conditions: Unprecedented observations

Aparna Das, Ajay K. Bose and Bimal Krishna Banik
Journal of the Indian Chemical Society, Vol.97(6), pp.917-925
01/06/2020

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
In this work we have investigated stereoselective synthesis of cis and/or trans beta-lactams under diverse conditions. Ten different reaction conditions have been used for this study. It is important to note that the stereochemistry of the beta-lactam formation reaction depends on the conditions of the experiments, structures of the imines and acid chlorides, order of addition of the reagents, reaction temperature and solvents. To summarize the results, mathematical graphs are plotted.

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