Stereoselective synthesis of short benzyl malonyl peptides

Emanuele Aresu; Stefania Fioravanti; Simona Gasbarri; Lucio Pellacani; Fabio Sciubba

doi:10.1039/c3ra41852a

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Stereoselective synthesis of short benzyl malonyl peptides

Journal article

Peer reviewed

Stereoselective synthesis of short benzyl malonyl peptides

Emanuele Aresu, Stefania Fioravanti, Simona Gasbarri, Lucio Pellacani and Fabio Sciubba

RSC advances, Vol.3(32), pp.13470-13476

01/01/2013

DOI: https://doi.org/10.1039/c3ra41852a

Abstract

Chemistry

Chemistry, Multidisciplinary

Physical Sciences

Science & Technology

A Rh-catalyzed addition reaction on non symmetric dehydro alanine retro-peptides is the key step in the reported three-step strategy for the diastereoselective synthesis of differently functionalized benzyl malonyl peptides (74% overall yield).

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Title: Stereoselective synthesis of short benzyl malonyl peptides
Creators - without role: Emanuele Aresu - Sapienza University of Rome
Stefania Fioravanti - Sapienza University of Rome
Simona Gasbarri - Sapienza University of Rome
Lucio Pellacani - Sapienza University of Rome
Fabio Sciubba - Sapienza University of Rome
Publication Details: RSC advances, Vol.3(32), pp.13470-13476
Publisher: Royal Soc Chemistry
Number of pages: 7
Grant note: Universita degli Studi di Roma "La Sapienza"
Identifiers: 9945328208331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article