Abstract
The aim of this paper is to fully exploit the medical potential of α‑Fe2O3 as a promising material for anticancer agent. Herein, Fe2O3 nanoparticles (NPs) have been synthesized using thermal decomposition method for the iron(III) Schiff base (N,N′‑disalicylidene‑l,2‑phenylenediamine (H2dsp), N,N′‑disalicylidene‑3,4‑diaminotoluene (H2dst), 4‑nitro‑N,N′‑disalicylidene‑1,2‑phenylenediamine (H2ndsp) and N,N′‑disalicylidene ethylenediamine (H2salen)) complexes as precursors. The calcined of Fe2O3 NPs were comprehensively characterized based on UV–Vis, FT-IR, SEM, TEM and XRD. The band gap energy of the synthesized α‑Fe2O3 NPs particles are 1.75–1.92 eV range. Evaluation of cytotoxicity against human breast cancer cell line (MCF-7) for the synthesized α‑Fe2O3 hematite nanoparticles was performed.
•Fe2O3 NPs have been synthesized using iron(III) Schiff bases precursors.•Fe2O3 NPs were discussed using UV–Vis, FT-IR, SEM, TEM and XRD.•Band gap energy of the Fe2O3 NPs particle located within 1.75–1.92 eV range•Cytotoxicity of synthesized Fe2O3 against MCF-7 cell line was assessed.