Abstract
Supercritical fluid extraction (SFE) achieves a wide range of applications since the past decade as a sustainable green technology. The present study investigates the process for producing high yield by supercritical carbon dioxide (Sc-CO
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) extraction form Gymnema sylvestre R.Br. roots. The effect of temperature and pressure on the percentage of accumulative yield is demonstrated. It is found that the highest yield is obtained at the temperature of 60°C and the pressure of 10 MPa. A proper review showed that there is a lack in the study of Sc-CO
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extraction of this plant especially for optimization of SFE process which makes this study useful and valuable. For more benefit, the extract which achieves highest percentage is subjected to gas chromatography-mass spectrometry to study its chemical composition and detect the active principle compounds which present with high concentration and expected to be responsible of the pharmaceutical properties of the extract.