Abstract
The Commiphoraquadricincta, a small tree, belong to Burseraceae family is traditionally known for its medicinal properties. The present study was therefore carried out to investigate the synergistic antimicrobial activities and the Phytochemicals of the bioactive components in the extract of this plant species. The antimicrobial activities of stem, bark and leaves extract was investigated against 7 medically important bacterial strains, namely Bacillus subtilius, MRSA, Micrococcus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aurues and Klebsellapneumoniae and five fungi (Aspergillusniger, A. fumigatus, A. flavus, Candida albicansand Saccharomyces spp). The antibacterial activity was determined using agar well diffusion method. The most susceptible bacteria to this extract was Escherichia coli, while the most susceptible fungi was A. flavus. GC-MS analysis revealed that the ethanol extract of Commiphoraquadricincta contained mainly; 2Methyl3pentanol (2.84%); Butyl hydroxytoluene (22.32%); 9,12,15Octadecatrienoic acid, 2-phenyl-1, 3-dioxan-5-yl ester (5.90); Ethyl isoallocholate(11.21%); aAmyrin (2.22%) and Flavone 4'oh,5oh,7dioglucoside(11.21%). Most identified compounds are known to have antimicrobial activity.