Abstract
Abstract
(3S,4S)-3-Methyloctan-4-ol,
(4S,5S)-4-methylnonan-5-ol,
and (+)-TRANS-whiskey lactone [(4S,5R)-5-butyl-4-methyldihydrofuran-2(3H)-one] were
synthesized stereoselectively by using a radical cyclization reaction
as a key step. All three molecules were synthesized from a common
cyclic acetal intermediate.