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Syntheses of Hydrazino Peptides and Conjugates
Journal article   Peer reviewed

Syntheses of Hydrazino Peptides and Conjugates

Siva S. Panda, Claudia El-Nachef, Kiran Bajaj and Alan R. Katritzky
European journal of organic chemistry, Vol.2013(19), pp.4156-4162
01/07/2013

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
(alpha-Benzyloxycarbonyl-aminoacyl)benzotriazolides (Cbz = benzyloxycarbonyl) underwent a coupling reaction with -hydrazino acids under microwave irradiation to form hybrid hydrazino dipeptides (42-71%). Chiral acylations of -N-Cbz--hydrazino acylbenzotriazolides were successfully carried out with N-, S-, O-, and C-nucleophiles in yields of 49-88%.

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