Abstract
The new homoleptic [Ag(5-nitroquinoline)(2)]ClO4 centrosymmetric complex was synthesized and its structure aspects were investigated. It crystallized in the monoclinic space group C2/c with a = 10.0279(2) angstrom, b = 13.2295(3) angstrom, c = 14.7552(3) angstrom and beta = 102.1050(10)degrees while V = 1913.96(7) angstrom(3) and half molecule as asymmetric formula. The Ag(I) is coordinated with two symmetrically related 5-nitroquinoline ligand units via the heterocyclic nitrogen atom with Ag-N distance of 2.146(6) angstrom and N1-Ag-N1 angle of 173.0(3)degrees. The two coordinated 5-nitroquinoline have anti configuration to one another and the perchlorate anion is set freely uncoordinated. The only Ag horizontal ellipsis O interactions are Ag1 horizontal ellipsis O2 (3.110 angstrom) and Ag1 horizontal ellipsis O1 (3.189 angstrom) which occur between the Ag(I) in one complex unit and the O-atoms from the NO2 groups in the neighbouring complex units. Hence, Ag(I) has coordination number 2 and its coordination geometry is slightly bent. Hirshfeld analysis indicated that the O horizontal ellipsis H (51.1%), C horizontal ellipsis H (11.8%), H horizontal ellipsis H (10.8%) and C horizontal ellipsis C (8.9%) contacts are the most common. Exclusively, the O horizontal ellipsis H, C horizontal ellipsis O, N horizontal ellipsis O, O horizontal ellipsis O and Ag horizontal ellipsis O contacts are the only shorter contacts than the vdWs radii sum of the interacting atoms. The studied Ag(I) complex showed good antimicrobial activity. It has comparable antibacterial activity against P. vulgaris (MIC = 9.7 mu g/mL) and S. aureus (39.1 mu g/mL) to Gentamycin (4.8 and 9.7 mu g/mL, respectively) while better antifungal activity against A. fumigatus (MIC = 39.1 mu g/mL) than Ketoconazole (156.2 mu g/mL).