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Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides
Journal article   Peer reviewed

Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides

Aamer Saeed, Sabah Zaman, Maryam Jamil and Bushra Mirza
Turkish journal of chemistry, Vol.32(5), pp.585-592
01/01/2008

Abstract

Chemistry Chemistry, Multidisciplinary Engineering Engineering, Chemical Physical Sciences Science & Technology Technology
Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.

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