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Synthesis and Antimicrobial Activity of Some Heterocyclic 2,6-Bis(substituted)-1,3,4-thiadiazolo-, Oxadiazolo-, and Oxathiazolidino-Pyridine Derivatives from 2,6-Pyridine Dicarboxylic Acid Dihydrazide
Journal article   Peer reviewed

Synthesis and Antimicrobial Activity of Some Heterocyclic 2,6-Bis(substituted)-1,3,4-thiadiazolo-, Oxadiazolo-, and Oxathiazolidino-Pyridine Derivatives from 2,6-Pyridine Dicarboxylic Acid Dihydrazide

Said A. S. Ghozlan, Mohammed A. Al-Omar, Abd El-Galil E. Amr, Korany A. Ali and Ahmed A. Abd El-Wahab
Journal of heterocyclic chemistry, Vol.48(5), pp.1103-1110
01/09/2011
DOI: https://doi.org/10.1002/jhet.690

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
In this work, we report on the synthesis and preliminary biological activity screening of several heterocyclic derivatives 2-15 based on N2',N6'-diphenylthiosemi-carbazide pyridine-2,6-dicarbohydrazide 2, which has been obtained from the corresponding dihydrazide 1. The biological screening showed that many of these compounds have good antimicrobial activities. The structure of the new compounds has been established on the bases of chemical and spectroscopic evidences.

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