Abstract
Background: A series of novel substituted 3-(thiophen-2-yl) pyrazoles was synthesized efficiently and in high yields using simple and convenient procedures starting from 1-phenyl-3(thiophen-2-yl)-1H-pyrazole-4-carbaldehyde.
Methods: The structures of the newly synthesized products were established and their antimicrobial activities were investigated against some bacteria and fungi.
Results and Conclusion: The products showed excellent antimicrobial activities against the tested microorganism compared to the standard antibacterial and antifungal drugs.