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Synthesis and Antitumor Evaluation of Novel Alkylated Hydantoin and Thiohydantoin Derivatives
Journal article   Peer reviewed

Synthesis and Antitumor Evaluation of Novel Alkylated Hydantoin and Thiohydantoin Derivatives

A. H. Ahmed, A. Ebead, H. Afifi, A. A. -H. Abdel-Rahman and A. H. M. E. D. A. M. AHMED
Russian journal of general chemistry, Vol.89(2), pp.357-363
01/02/2019
DOI: https://doi.org/10.1134/S1070363219020294

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
New alkylated hydantoin as well as 2-thiohydantoins were synthesized for broadening the library of compounds screened for antitumor activity. Antitumor activity of the new compounds was evaluated against breast cancer cell line (MCF-7) and demonstrated moderate to good activity.

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