Abstract
The synthesis of novel heterocyclic aryl monoazo organic compounds, including 3-amino-4,6-dimethyl-N-(5-arylazothiazol-2-yl)selenopheno[2,3-b]pyridine-2-carboxamide, 3-amino-4,6-diphenyl-N-(5-arylazothiazol-2-yl)selenopheno[2,3-b]pyridazine-2-carboxamide and 3-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-N-(5-arylazothiazol-2-yl)selenopheno[2,3-b]quinoline-2-carboxamide using a condensation reaction involving different 2-(N-chloroacetyl)-5-arylazo-thiazole derivatives with seleno derivatives of pyridine, pyridazine, and/or quinolone, respectively, was undertaken. Analytical and spectroscopic data confirm the proposed structures. The novel synthesized thiazole-selenium disperse dyes were applied for dyeing polyester fabrics. Color characteristics and fastness properties were investigated. The novel synthesized compounds exhibited high efficiency based on in vitro screening of their antioxidant activity, antitumor activity against Ehrlich ascites carcinoma cell EACC cell line and antimicrobial activity against various pathogenic bacteria and fungi. The colored polyester fibers could be applied as sterile and/or biological active fabrics used in various life applications.