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Synthesis and Biological Evaluation of New Fused Isoxazolo[4,5-d] Pyridazine Derivatives
Journal article   Open access  Peer reviewed

Synthesis and Biological Evaluation of New Fused Isoxazolo[4,5-d] Pyridazine Derivatives

Hassan M. Faidallah, Khalid A. Khan and Mohammed S. I. Makki
Journal of the Chinese Chemical Society (Taipei), Vol.58(2), pp.191-198
01/04/2011
DOI: https://doi.org/10.1002/jccs.201190076

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Three new heterocyclic ring systems, isoxazolo[4,5-d]-1,2,4-triazolopyridazines 12-15, tetrazolo-[4,3-b]pyridazine 18 and isoxazolo[4,5-d]pyridazino[2,3-c]2H-triazines 16,17 along with isoxazolo[4,5-d]pyridazines 2, 5-10 have been synthesized. Preliminary screening of these tricyclic heterocycles revealed that some of them possess significant antibacterial and antifungal activity.
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https://doi.org/10.1002/jccs.201190076View
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