Abstract
Pyrimidino[5`,4`-6,5]-,pyridino[3`,2`-6,5]- and pyrrolo[3`,2`-5,6]4H-pyrano-[3,2-c][
1
]benzopyran-6-one derivatives (
5-7
and
10
) could be obtained via reaction of 2-amino-4-(
p
-bromophenyl)-3-cyano(carboethoxy)-4H,5H-pyrano[3,2-c][
1
]benzopyran-5-ones (
3a,b
)with a variety of reagents. Alkylation of (
3b
) with either 2-furoyl chloride or chloroacetyl chloride gave the 2-
N
-substituted derivatives (
9a,b
). Benzofurano[3,2-b]4H-pyran derivative
(12
) was also prepared. The antimicrobial activity of the prepared compounds was tested.