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Synthesis and anti-HCV activity of beta-D-2 '-deoxy-2 '-alpha-chloro-2 '-beta-fluoro and beta-D-2 '-deoxy-2 '-alpha-bromo-2 '-beta-fluoro nucleosides and their phosphoramidate prodrugs
Journal article   Open access  Peer reviewed

Synthesis and anti-HCV activity of beta-D-2 '-deoxy-2 '-alpha-chloro-2 '-beta-fluoro and beta-D-2 '-deoxy-2 '-alpha-bromo-2 '-beta-fluoro nucleosides and their phosphoramidate prodrugs

Reuben Ovadia, Ahmed Khalil, Hao Li, Coralie De Schutter, Seema Mengshetti, Shaoman Zhou, Leda Bassit, Steven J. Coats, Franck Amblard and Raymond F. Schinazi
Bioorganic & medicinal chemistry, Vol.27(4), pp.664-676
15/02/2019
PMCID: PMC6425950
PMID: 30655167

Abstract

Biochemistry & Molecular Biology Chemistry Chemistry, Medicinal Chemistry, Organic Life Sciences & Biomedicine Pharmacology & Pharmacy Physical Sciences Science & Technology
url
https://doi.org/10.1016/j.bmc.2019.01.005View
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