Abstract
Some novel derivatives of acylhydrazine such as; 5-substituted-2-mercapto-1,3,4-oxadiazoles 2a-g their corresponding S-esters 3a-g, amides 4a-g and benzenediazasulfonamides 6a-d have been prepared. Twenty four synthesized compounds were screened in vitro for their antibacterial and some for their antifungal activities. Minimum Inhibitory Concentration ( MIC) values of all the twenty four synthesized compounds were also determined. Some of the synthesized compounds exhibited significant antimicrobial activity.