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Synthesis and antimicrobial evaluation of some new pyrimidine derivatives
Journal article   Peer reviewed

Synthesis and antimicrobial evaluation of some new pyrimidine derivatives

Nabila A. Kheder, Yahia N. Mabkhot and Ahmad M. Farag
Heterocycles, Vol.75(4), pp.887-897
01/04/2008

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The utility of ethyl 6-methyl-2-oxo-4-phenyl-1,2-dihydropyrimidine5-carboxylate (1) in the synthesis of some new pyrido[1,2-f]pyrimidine, pyrazolo[3,4-b]pyrido[l,2-f]pyrimidine, 6-(4-substituted styryl)pyrimidine, pyrido[4,3-d]pyrimidine, pyrimido[5,4-d]pyridazine and substituted-6-(thien-2-yl)pyrimidine derivatives is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out.

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