Abstract
Facile routes were achieved for the synthesis of novel fluorinated spiro[oxindole-thiazolidinone] fused with some sulfur and phosphorus heterocycles starting from 5-fluoro-3'-(4-fluorophenyl)-4'H-spiro[indole-3,2'-thiazolidine]-2,4' (1H)-dione (1) via its reaction with trifluoroacetamide, 2-chloro-6-fluorobenzaldehyde and hydrazine hydrate followed by treatment with some suitable sulfur and phosphorus reagents. The antioxidant activities of the synthesized compounds were also evaluated.
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