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Synthesis and antioxidant activity of some thiazolidin-4-one derivatives
Journal article   Peer reviewed

Synthesis and antioxidant activity of some thiazolidin-4-one derivatives

Ahmed O. H. El Nezhawy, Mostafa M. Ramla, Nagy M. Khalifa and Mohamed M. Abdulla
Monatshefte für Chemie, Vol.140(5), pp.531-539
01/05/2009

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
4-Fluorobenzaldehyde was used for the preparation of 2-(4-fluorophenyl) thiazolidin-4-one derivatives which were allowed to react with chloroacetonitrile and acrylonitrile to produce 3-(2-(4-fluorophenyl)-4-oxothiazolidine3-yl) acetonitrile and 3-(2-(4-fluorophenyl)-4-oxothiazoledine-3-yl) propanenitrile. Biological evaluation of some of the compounds showed that many had promising antioxidant activity.

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