Abstract
6,8-dibromo-4H-3,l-benzoxazinone 2 is synthesized and allowed to react with some nitrogen nucleophiles namely, p-toluidine, hydroxylamine hydrochloride, ethanolamine, and glycine and affords 3-substituted quinazolinones 3-6, while with isobutylamine and benzylamine results benzamide derivatives 7,8. Compound 4 is subjected to acylation and alkylation and produces 9-11 respectively. Alkylation of compound 5 with 2-naphthol and benzamide yields 12,13. Treatment of benzoxazinone 2 with o-phenylenediamine in different solvents under different conditions affords the substituted benzamide 14 and 3 -substitutedquinazolinone 15.