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Synthesis and biological activity of heterocycles from chalcone
Journal article   Peer reviewed

Synthesis and biological activity of heterocycles from chalcone

Zeba N. Siddiqui, Mohammad Asad and Shagufta Praveen
Medicinal chemistry research, Vol.17(2-7), pp.318-325
01/06/2008

Abstract

Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
The chalcone 3 was synthesized from 3-acetyl-4-hydroxy coumarin and 3-formylchromone by refluxing in ethanol in the presence of a catalytic amount of pyridine. 3 was converted to bipyrazoles 4a-b by treatment with hydrazine and phenylhydrazine. The compounds were screened for their antibacterial activity.

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