Abstract
The objective of this work was to set up a method to formulate a complex for the assessment of myocardial infarction in vivo. Labetalol was successfully labeled with Tc-99m using SnCl2 center dot 2H(2)O as reducing agent. Various reaction parameters were investigated to optimize the labeling yield. The labeled complex was stable for up to 24 h. The heart uptake was 35.5 % ID/Organ at 5 min post-injection, while the clearance pathways from the body behave via both the hepatobiliary and renal routes.