Synthesis and biological evaluation of novel dibenzofluorene derivatives as anticancer agents

BIMAL K. Banik; CHHANDA Mukhopadhyay; FREDERICK F. Becker

doi:10.3892/ol_00000055

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Synthesis and biological evaluation of novel dibenzofluorene derivatives as anticancer agents

Journal article

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Peer reviewed

Synthesis and biological evaluation of novel dibenzofluorene derivatives as anticancer agents

BIMAL K. Banik, CHHANDA Mukhopadhyay and FREDERICK F. Becker

Oncology letters, Vol.1(2), pp.309-311

01/03/2010

DOI: https://doi.org/10.3892/ol_00000055

PMCID: PMC3436464

PMID: 22966300

Abstract

anticancer agent

biological evaluation

dibenzofluorene

synthesis

The novel synthesis of dibenzofluorene has been achieved by a cyclodehydration method. Several derivatives have also been prepared using this hydrocarbon. These compounds have been tested against a number of cancer cell lines in vitro, and useful selectivity has been observed.

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Title: Synthesis and biological evaluation of novel dibenzofluorene derivatives as anticancer agents
Creators - without role: BIMAL K. Banik - Department of Chemistry The University of Texas-Pan American Edinburg TX, 78539.
CHHANDA Mukhopadhyay - Department of Chemistry, The University of Texas-Pan American, Edinburg, TX 78539 Department of Molecular Pathology, Unit 951, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77504, USA
FREDERICK F. Becker - Department of Chemistry, The University of Texas-Pan American, Edinburg, TX 78539 Department of Molecular Pathology, Unit 951, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77504, USA
Publication Details: Oncology letters, Vol.1(2), pp.309-311
Publisher: D.A. Spandidos
Identifiers: 9924823808331
Academic Unit: Prince Mohammad Bin Fahd University
Language: English
Resource Type: Journal article